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frozen with words in UR mouth
Isacc is isolated solid and stoned
isolate by Jacques Alfonso February 18, 2003

isolate the variable 

the act of focusing on an appealing portion of a person's body with a general disregard for the undesirable regions
Steve: Could you isolate the variable on that?
John: You know it. She's huge, but those are some mighty fine sweater cows.

Bill: You see that?!?!
James: You serious? She's hideous.
Bill: C'mon you gotta isolate the variable.
James: You right. She needs to turn back around though.
isolate the variable by tmack41 December 7, 2011

self-isolate 

A crappy excuse to tell your boss that you would rather stay at home watching porn and eating that pasta you’ve been stockpiling
Employee: Sorry, I don’t think I can come to work today, I need to self-isolate
Boss: (sarcastically) Right
self-isolate by massivetraps25 March 19, 2020

Triracial Isolate 

A Triracial Isolate community is a community of people who have been mixed, a genetic mix of 3 different races, for several generations, developing their own unique identity and culture. They're common in countries that went through European colonialism, like in the USA where some 400+ triracial isolate groups of various sizes reside. The Sweetgum Kriyuls are most well-known, being a group of triracial isolates in the Southern and Eastern USA, divided into tribes such as the Melungeons, Lumbees, Moors of Delaware, Ethnic Qarsherskiyan, and Marlboro Blue Tribe.
Triracial Isolate groups like the Melungeons, Lumbees, and Qarsherskiyans are more influential on America than most people realize. Elvis Presley was a Melungeon. So is JD Vance.

italian isolation 

to be in a small shower naked with 4 italian girls while they wash eachother
"what did you guys do last night?"

"oh just some italian isolation."
italian isolation by el fen August 18, 2009

Isolating Yourself 

When you hide in corners, keep to yourself excessively, like to be alone and are slightly scared of people.
Doctor: Anya, stop isolating yourself. You're going to become a hermit.

Anya: OK. (Makes a weird noise and runs out of the room, slamming the door behind her and locking herself into the bathroom)