mispronunciation of the word 'south' mostly by eastern Europeans who lack the ability to annunciatethe English 'th' sound.
Shawn: Yo, man I want to come down so we can get some cheesesteaks on the boardwalk Jeff: Cool get your cotz (see def.) on the Parkway Souse and get off at 82A
Martin: howsitgoin
A bodily substance found to be highly desireable by the Skeezix in the old Uncle Wiggily stories. Connotation is not vulgar or nasty. "Souse" was never described or defined, just referred to in a threat.