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A particularly nasty STD, that in later stages causes infertility, leads to your pubes falling out and eventually insanity and death. Friedrich "God is dead" Nietzsche, the German philosopher, caught this from a whore and died. Very common in the midle ages, particularly among the nobility of France. Can be covered up, externally, by a merkin. The US government conducted secret tests on African-Americans in the 30's to see how likely you were to die from syphilis. The Tuskegee Syphilis Experiments didn't end until the 1970's.
I didn't use a condom when I had sex with that whore and now I have tertiary syphilis, which is making me CRAZY! This is some bad news for my poor wang.
Syphilis by me oh my December 28, 2005
1. noun. a sexually transmitted disease that results in stinging warts, excessive stinging while urinating, and possibly bleeding from the pee hole...

2. noun. what i named my hamster in 6th grade
1. your fucking sister gave me syphilis! no wonder she was so easy!

2. rest in peace syphilis, you were so cute

remember kids, wear a condom
syphilis by wrong or right? April 20, 2007
Kenny McCormick died of syphilis after getting a BJ at TGI Friday's
syphilis by L0Ljoker124 October 21, 2010
an STD whose origin is traced back to the vaginal tract of llamas
When the Mexican sailors became desperate, they resorted to banging llamas, hence starting the spread of syphilis.
syphilis by NikiAna May 28, 2008
The classiest of STDs. One is said to see a bow-tie on this STD when examined under a microscope.
"That hoe is so classy she must have syphilis".
Syphilis by Matt Van Natta September 16, 2010
Matt Jannsens had sex with some hog (ashley nutting) and contracted Syphilis. Word.
Syphilis by xB00-RADLEYx September 23, 2009