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A mix between autism and down syndrome
he has downism
Downism by PPGOD June 16, 2018
Related Words

Downtism 

N).a very rare disease that was spread in the mid 1800's which is a mixture of autism and down syndrome but was later cured; although it has come back from the source downteccia aka D. Laveieri.

N).Some one that is really dumb.

alternate uses Downtistic
Dude daneille has a major case of downtism and needs to be institutionalized immediatly
Downtism by squigz April 25, 2008

Downtism 

somebody so stupid that you are convinced they have Down syndrome and Autism.
"I'm convinced that who ever shot Harambe has Downtism."
Downtism by yesuwuceg June 17, 2017

downtism 

Guy who’s name is Kai, and snorts gas lighter fluid.
When you snort gas lighter fluid you get downtism
an accidental activity whereby a person destroys everything in their path, in a comic way.
Billy falls over breaking 5 glasses.

Tina: That is such a donism Billy.
donism by donskin August 5, 2008

Downsmile 

1. (n) To frown.
"Never let em' see you downsmile while you bleedin'!" - K'naan in the song Smile from his Dusty Foot Philosopher album
Downsmile by RevolutionK January 10, 2011