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To make incredibly bad bets which you can't cover. To such a degree that it could fuck up everything in the known world.

As when Melvin Capital engaged in naked short selling causing historic losses and a global financial crisis in 2021.
Holy shit we just Melvined the whole fucking thing.
Melvined by PuppetJustice November 20, 2021
To be scammed by someone who is clueless they're clueless.
Dr. Paul: "Hi Lori, you're looking a little upset this morning. Care to talk about it?" "Oh Dr. Paul...I don't know what to do...this guy Melvin... just cost me hundreds of dollars in service fees by lying to my credit card provider, telling them I never sent him his order. But I did...I really did. I had all my paperwork work proving I did, but the bank took his side regardless and won't pay me. I've been...oh....ahhhh...I've been Melvined"....

Melvindale

The small, once peaceful city, that was invaded by Detroiters, basically ruining the city, especially the schools. Melvindale is mainly known for a lady stabbing her dad over a dinner roll, a drunk 14 year old being raped, and a racist former high school football coach. Melvindale is one step away from becoming a ghetto. They might as well give up and make it another part of Detroit.
Where do you live?" "My crib be in dat sity Melvindale
Melvindale by sosickofthishittt December 9, 2010

Melvindale

A small, obnoxious city on the cusp of Detroit in Michigan. Part of a region referred to as "Downriver". Generally has a bad reputation within the area.
I can't believe that guy was from Melvindale. He could string together multiple sentences!
Melvindale by daegan August 11, 2008

Melvindale High School 

Melvindale High School, the worst highschool in the downriver area of Michigan. This school is known for its fake, drama-starting, ghetto, copy-cating, and ignorant kids. The teachers are also very lazy and show alot of favoritism. The custodians don't do their jobs because the rooms and restrooms are filthy. The food is also terrible, you could get a better meal in jail. The girls at the school are either really ghetto, dumb, fake, or nasty. The black kids at the school act like everybody is supposed to bow down to them or act as ghetto they do. I would advise not sending your kid to Melvindale High School or attend the school yourself. If you decide to go to this school you will have the worst time of your life.
Melvindale High School by Fmhs777 November 13, 2011

Melvinesque 

1. Melvin-like
2. Like a Melvin.
Mike was displaying a very melvinesque behavior whilst taking strokes off his golf game.
Melvinesque by Melvin Melvinson August 30, 2012