1. something that crosses two or more states
2. the name of a few highways in the U.S.
We are arriving at Interstate 210, please be ready to unbuckle. This is a bus rest station and this is your chance to go to the restroom, or buy something to eat.
synonyms: strenuously, with great vigor, strongly, powerfully, potently, forcefully, with force, forcibly, energetically, aggressively, heartily, eagerly, with eagerness, enthusiastically, with enthusiasm, with great effort, with all one's might, with might and main, with a will, for dear life, for all one is worth, to the best of one's abilities, as best one can, all out, with a vengeance, fiercely, intensely, hard, as hard as possible, as hard as one can, with all the stops out, like the devil, like the deuce, at full tilt;
He strummed the strings vigorously.