n. Pharmaceuticals courier.
Dude, Pedro the mule just checked in. Let's 420 !
by D'emon November 8, 2002
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To carry, in one's anal cavity, any contraband, i.e. illicit drugs.
"Jorge muled the baggie of yeyo across the US border, but his anus hurt afterwards."
by Anthony Jaketti February 3, 2005
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Someone that is generally incompetent. Opposite of a thoroughbred.
I don't know how the new director got his job. He sure is one dumb mule.
by thaddeus February 5, 2004
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To stick false teeth up ones ass, and then later shit them out on a females tits.
I didnt feel like takin her shit so i muled the fuck outta her.
by Cran December 8, 2004
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To smuggle an object by hiding it in your ass.
Security wouldn't let me take my camera in to the game so I had to mule it.
by iam2eeyore December 3, 2009
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A beautiful Sicilian last name, pronounced (Mu lay)
Giuseppe mule is a very respectable sicilian.
by TraceyMolly March 9, 2006
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A person alientated from a group or activity. Usually shouted at that person to make them feel worse, and increase their understanding of their alienation
"Hey, look at Richard over there! He's totally off by himself. MULE!"
by Dix McGee May 19, 2006
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