Top Definition
Any Lazy douche bag that cannot be counted on to even breathe on a regular basis.

Plural: Lopii
That fat Lopus said they were going to be here.

A) They played like shit.

B) What did you expect they're a bunch of Lopii
by Only Ace April 29, 2009
medical condition
he has lopus
by sherrydeb September 07, 2003

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