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It's an essence extracted from someone's skull at the point of death.

It's highly euphoric and addictive. You don't feel anything while it's inside of you.

Amber Sweet (Paris Hilton) is addicted to it in Repo! The Genetic Opera. She has a sexual relationship with G-Rob who she gets it from.

It's generally used before getting surgery.

Though, it's highly abused.
(From Zydrate Anatomy)
GRAVEROBBER
Zydrate comes in a little glass vial.

SHILO
A little glass vial?

CROWD
A little glass vial!

GRAVEROBBER
And the little glass vial goes into the gun like battery.
And the Zydrate gun goes somewhere against your anatomy
And when the gun goes off, it sparks and you're ready for surgery.
Zydrate by NoahtheGreat October 31, 2008
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Zydrate is a fictional drug. In the movie Repo! The Genetic Opera, Zydrate -a potent opioid extracted from dead bodies- is manufactured by GeneCo. as a prescription painkiller. Zydrate is injected with a Zydrate-Gun which uses an electric current to enhance the drug's analgesic effect.
Graverobber: Zydrate comes in a little glass vile.

Shilo: A little glass vile?

Junkies: A little glass vile!

Graverobber: And the little glass vile goes into the gun like a battery... And the Zydrate-Gun goes somewhere against your anatomy... And when the gun goes off it sparks and you're ready for surgery.
Zydrate by LJenna January 5, 2009
Related Words
A mixture of Mountain Dew Voltage and ecstasy (MDMA). Named after and inspired by the fictional drug of the same name from the movie Repo! The Genetic Opera.
Hey dude, I made some zydrate from some ecstasy we got at the club the other night.
Zydrate by Jehav July 2, 2009
Zydrate is a rare type of drug that helps relieve pain. It also gets you a bit high. Mainly scalpel sluts use this drug.
Amber Sweet is addicted to the knife, so in order for her to relieve her pain, she buys Zydrate from a Grave Robber.
Zydrate by xxRepoManxx January 16, 2009
More from Urban Dictionary
A dead drop is a location used to secretly pass items between two people, without requiring them to meet.

Spies have been known to use dead drops, using various techniques to hide the items and to signal that the drop has been made. Drug dealers use this as well.

A common place is to duct tape the item to the underside of a toilet cover in a public restroom.

A signal is sometimes used as well to indicate there is something to pickup, like a pile of stones in a certain formation. After checking the drop the signal is removed.
"The dead drop is the restroom toilet at the Gulf station at the corner of Commercial Ave. and Georges Rd."
dead drop by rubberroom July 23, 2008
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This designation comes from Reddit, where so many stories of bad wedding behavior indicated a need to communicate expectations for the wedding behavior of attendees.
You are cordially invited to the nuptials of Brian and Tom on October 31 at noon.

Please note that this wedding is child-free (under 10) and a No Surprises Wedding (NSW). Reach out to wedding planner Sami Smith to request approvals or exceptions; please note that exceptions will be rare. Limited child care for under-10s will be available. All approvals will be noted and included in planning. Unapproved, or surprise exceptions, will result in guests being asked to leave.
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"Hey, see that chick over there? She's pretty enough to be an ulzzang. :D"
ulzzang by `r i k kit t y February 26, 2008
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