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It's an essence extracted from someone's skull at the point of death.

It's highly euphoric and addictive. You don't feel anything while it's inside of you.

Amber Sweet (Paris Hilton) is addicted to it in Repo! The Genetic Opera. She has a sexual relationship with G-Rob who she gets it from.

It's generally used before getting surgery.

Though, it's highly abused.
(From Zydrate Anatomy)
GRAVEROBBER
Zydrate comes in a little glass vial.

SHILO
A little glass vial?

CROWD
A little glass vial!

GRAVEROBBER
And the little glass vial goes into the gun like battery.
And the Zydrate gun goes somewhere against your anatomy
And when the gun goes off, it sparks and you're ready for surgery.
Zydrate by NoahtheGreat October 31, 2008
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Zydrate is a fictional drug. In the movie Repo! The Genetic Opera, Zydrate -a potent opioid extracted from dead bodies- is manufactured by GeneCo. as a prescription painkiller. Zydrate is injected with a Zydrate-Gun which uses an electric current to enhance the drug's analgesic effect.
Graverobber: Zydrate comes in a little glass vile.

Shilo: A little glass vile?

Junkies: A little glass vile!

Graverobber: And the little glass vile goes into the gun like a battery... And the Zydrate-Gun goes somewhere against your anatomy... And when the gun goes off it sparks and you're ready for surgery.
Zydrate by LJenna January 5, 2009
Related Words
A mixture of Mountain Dew Voltage and ecstasy (MDMA). Named after and inspired by the fictional drug of the same name from the movie Repo! The Genetic Opera.
Hey dude, I made some zydrate from some ecstasy we got at the club the other night.
Zydrate by Jehav July 2, 2009
Zydrate is a rare type of drug that helps relieve pain. It also gets you a bit high. Mainly scalpel sluts use this drug.
Amber Sweet is addicted to the knife, so in order for her to relieve her pain, she buys Zydrate from a Grave Robber.
Zydrate by xxRepoManxx January 16, 2009
Cigarette: Northern slang for a cigarette, used oft by mashed up mancunian ravers becasue of the resemblance of a hot(electric)stove to the end of a lit cigarette. Originated circa 1991 in the early halcyon days of the rave culture; we speculate during a drug fuelled hallucination by said manc.
'fuck me noel, i am bolloxed, is that a ciggy in your mouth, or the stove from me 'nans kitchen'/
General use: 'Give us a stove you cunt'
stove by anthony willison March 18, 2004
Word of the Day on August 4, 2026

Walky-Talky 

A derogatory term for able bodied people or people that can walk. This definition was coined by disabled influencer Valerie Weber
Person in wheelchair: “look at that walky-talky over there.”

Friend in wheelchair: *looking at person who is walking* “yeah haha
Walky-Talky by odd muffin October 5, 2021
Word of the Day on August 3, 2026

Scrapnel 

(N) :
All pieces left over after an art project or home improvement.
"After we made the decorations for the party, there was 'scrapnel' all over the floor"
Scrapnel by IceSniper February 22, 2025
Word of the Day on August 2, 2026