vamoose 

to instantly disappear, make as though it never was.

Izzo- H to the Izzo V to the Izza. he who does not feel is not real to me, and therefore does not exist... so poof vamoose son of a bich (South park movie reference)

vamoose by blink fanatic January 12, 2005

vamoose 

to leave or depart hastily (from Spanish, Vamos meaning let us depart)

I've gotta vamoose or I'll be late.

vamoose by The Return of Light Joker June 30, 2009

vamoose 

Scram, take off, go away, gtfo.

Comes from the Spanish vamos - the word transitioned into American English as a result of contact with the Spanish colonies in Mexico.

Trust me holmes, you don't want to start shit with me. Vamos, esse.

vamoose by Tronno August 27, 2005

vamoose 

Be gone;leave

Jay-z's Song "poof, vamoose son of a bi***"

vamoose by Ariana March 29, 2004

vamoose 

Move now, get out of here, move your bottom please.

Gardener to flock of distructive birds: vamoose you darn birds!!

vamoose by crayola March 30, 2004

vamoose 

Make an expedited departure. scram

You - you're bugging me. Vamoose.

vamoose by DHG March 30, 2004

vamoose 

To disappear.

You'd better vamoose before my girlfriend catches us.

vamoose by LB March 31, 2004