twisty-wisty Share definition Flag when a girl grabs a males reproductive extremely hard, then proceeds to twist it into what feels like a dog ballon. "yeah Rebecca gave me that twisty-wisty after I told her she was a bitch." twisty-wisty by Saxtton September 27, 2020 0 0 Get merch Get the twisty-wisty mug. Buy Now — $32.95 See more merch