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The resulting burn on the roof of your mouth from eating hot pizza before it has cooled to a non-harmful temperature.
Charlie was so hungry that he took a huge bite of pizza after it came out of the oven. The boiling cheese scalded his pie hole and he got pizza burn.
by el Jefe Designs March 24, 2011
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A second degree burn attained when you're biting into pizza and the hot skin on top slides off the dough, hanging off your mouth and burning your lip like fucking Satan.

Requires medical attention.
Eric: Dude, where have you been all week?
James: Sorry, I just came out of the hospital after a Pizza Burn.
Eric: Holy shit, so that explains why half of your face is missing.
by DontEatThatBacon June 19, 2016
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