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1. To commence an undertaking.

2. To beat the crap out of someone.

3. To fuck wildly.

4. To turn the tables during an Ultimate Frisbee game.

1. We should really open up shop on Project Apollo.

2. If he keeps pissing me off, I'm gonna open up shop on that asshole.

3. Dude, she's hot. I'd definitely open up shop on her.

4. We were losing pretty badly until we gave up the zone defense and opened up shop on them.
by thaks April 09, 2006
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