Verb.

1. To commence an undertaking.

2. To beat the crap out of someone.

3. To fuck wildly.

4. To turn the tables during an Ultimate Frisbee game.
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1. We should really open up shop on Project Apollo.

2. If he keeps pissing me off, I'm gonna open up shop on that asshole.

3. Dude, she's hot. I'd definitely open up shop on her.

4. We were losing pretty badly until we gave up the zone defense and opened up shop on them.
by thaks April 10, 2006
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At the track totally dominating the competition with the best setups.
JHM and VAST going to the track and they open up shop on AWE/GIAC
by Jason Harbinson August 17, 2007
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When two people are going to have a disagreement. As in, "there's enough beef between us to open up a butcher shop".
Mike: Oh shit, Bobby stole Jimmy's girl.
Dan: Those guys are going to open up a butcher shop.
by LaffeyTaffy June 15, 2012
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