The word mofo is used as a shortened version of mother fucker.
Yo Mofo... you steppin' on my turf now!
by Jade Maia June 2, 2008
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"Mofo" is a slang abbreviation for the word "motherfucker". However, unlike "motherfucker", "mofo" is used for humor instead of insult. This word is slowly becoming extinct, for it is no longer in style.
by Mr. Big C January 9, 2016
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shortened term for mother f***er
whats up mofo?
by big_ben100 September 13, 2009
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Of course, we call know that "mofo" is a more "polite" form of the word "motherfucker", just like the abbreviation "M.F.". "Mother" is also a substitute for that nasty word. "Mofo" is also the title of a song from the album "Pop", released by the band U2 in 1997. The song refers to Bono's mother, who died of cancer when Bono (Paul Hewson) was a teenager (Paul McCartney grew up with losing his mom in the same way). In the song Bono asks his dead mom "Mother, am I still your son?", and he asks her if she sees him on stage tonight and if she is proud of him. He does not sing the words "mofo", "motherfucker" or any related word in the lyrics. Maybe in a case of Irish humor, the song got its name as a parody of all the songs that feature the word "motherfucker" that saturated the market at the time, going on today.
1. That porno mag publisher is one sicko mofo, and he knows it, and he relishes that fact. He is proud to be an SMF.

2. When I saw U2 in concert in the spring of 1997, the 1979 classic by M called "Pop Music" was played, then came "Mofo", followed by "I Will Follow", then by several other U2 hits. Major kick ass.
by I Saw U2 Live Twice September 21, 2007
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Noun:

A true tearm of endearment. A conjunction for the term Mother Fucker. Could also be used for those drivers on the road who can't function in proper society, most likely from parenting styles or lack there of. One of the most versatile word you could use.
"That Mofo just fucked my ass hole".

"Hey Mofo, don't cut me off"

"Go eat a decroded piece of crap you stupid sick ass Mofo"
by Kanga Mangus Trickey D January 3, 2009
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Popularized on Jay Leno's "Headlines," short for "Morrison & Forrester," a law firm. The name was deemed too long, so they shortened it to "MoFo!"
"Where's my MoFo lawyer?!? You tell my MoFo lawyer to get his ass down here!!!"
by PheagleAdler January 24, 2010
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