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Eugene: Lordy, Yancy, why the hell are you grinning so big?

Yancy: I haven't pooped in eight days!

Eugene: Really, why is that?

Yancy: I killed a couple of bottles of Imodium last week. *wink*

Eugene: Oh.
Imodium by Pissant Fuckwad April 23, 2010

Imodium Maneuver 

(n) A technique where one decides not to cheat on his or her significant other by feigning an oncoming outbreak of diarrhea. The Imodium Maneuver allows one to save face and remain loyal to his or her significant other without insulting the other party or parties.
Pat was in a hot tub full of strippers and totally wanted to cheat, but then he used the Imodium Maneuver. The girls weren't insulted and he excused himself - everything was cool.
Imodium Maneuver by ColbertEagle November 3, 2010

Immodium Challenge 

A situation in which without taking Immodium, you will almost certainly shit yourself. Examples include situations of fear, embarrassment or extreme laughter in which you lose control over your bowels.
Man, I wish I popped an immodium because I diarrhea'd all over myself and the audience while walking the tightrope. That was true immodium challenge.
Immodium Challenge by matlin September 30, 2007
A combination of Imodium and Nexium or Prilosec. Imodium acts as an opioid similar to methadone when taken with PPI’s such as Nexium, it is sold in stores without prescription as it normally can not cross the blood-brain barrier. This is also why its used as a self-treatment for opioid withdrawal.
that imoxium be the best shit from cvs.
imoxium by 30_DOLLARHAIRCUT January 24, 2022

Immodium 

It is a Bluetooth butt plug for sticky situations. Mostly used in a pinch when shit wants to explosively leave your ass.
Hey mom, can I have some immodium. I have bad diarrhea.
Immodium by Socalmini February 3, 2024