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to show another person "whats up" or "what's happening".
to beat your opponent down in a fight or sport.
to display great skill at something.
to sexually satisfy a girl in bed.
to show her "what's up" or "what's happening".

"I played Bob in a game of Madden last week and was giving him the business. He lost 37-3."

"Ashley and I went out drinking last night. We started fooling around back at her place; next thing ya know I was giving her the business!"
by BigDaddyKen March 19, 2009
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2
In a American football game, it is punching or striking an opponent in the crotch. It is usually done during the pileup after a tackle or the pile after a fumble.
After Mark fumbled the ball, Sean was busy giving him the business.
by khalid_king_of_jews September 21, 2015
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