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Dysphoria is an experience trans, genderqueer, and non-binary people have. It describes discomfort, loathing, anxiety, and depression revolving around one's social gender role and/or physical sex characteristics. It's a very serious experience that leads to larger anxiety/depression problems, depersonalization, thoughts of suicide, social withdrawal, self harm, etc.
Fallon: Where were you last night? We missed you at the party.
Skylar: Sorry. I had a serious bout of dysphoria and couldn't bring myself to go.
Fallon: Oh, I understand. You didn't miss much, anyway.
by kyerowan January 16, 2014
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1. The opposite of euphoria.

2. An unpleasant situation or effects.
Tripping under the wrong conditions can cause one hell of a dysphoria.
by Sashie402 July 18, 2004
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The opposite of euphoria. It’s a mixture of depression, anxiety, rage, and despair.
I had a serious case of dysphoria after me n my girl broke up.
by artificialcherry February 20, 2009
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A state of unease or generalized dissatisfaction with life. Something that you must have in order to identify as Transgender or Non-binary.
"Micah's dysphoria is hitting them hard."
by heartbreaksofeden May 23, 2018
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