1. The opposite of euphoria.

2. An unpleasant situation or effects.

Dysphoria is an experience trans, genderqueer, and non-binary people have. It describes discomfort, loathing, anxiety, and depression revolving around one's social gender role and/or physical sex characteristics. It's a very serious experience that leads to larger anxiety/depression problems, depersonalization, thoughts of suicide, social withdrawal, self harm, etc.

The opposite of euphoria. It’s a mixture of depression, anxiety, rage, and despair.

A state of unease or generalized dissatisfaction with life. Something that you must have in order to identify as Transgender or Non-binary.