Dysphoria is an experience trans, genderqueer, and non-binary people have. It describes discomfort, loathing, anxiety, and depression revolving around one's social gender role and/or physical sex characteristics. It's a very serious experience that leads to larger anxiety/depression problems, depersonalization, thoughts of suicide, social withdrawal, self harm, etc.

1. The opposite of euphoria.

2. An unpleasant situation or effects.

The opposite of euphoria. It’s a mixture of depression, anxiety, rage, and despair.

A feeling that all transgender people get, whether they are mtf, ftm, or nonbinary.

Gender dysphoria | Feeling like you are a gender that is not the one you were assigned at birth.

Body dysphoria | Being uncomfortable with certain body parts because they remind you of the gender you do not identify as. Whether it be your no-no square or your feminine hips.

Social dysphoria | Discomfort in the gender the people around you see you as, and how they treat you based on that.

A state of unease or generalized dissatisfaction with life. Something that you must have in order to identify as Transgender or Non-binary.

A state of dissatisfaction with life in general. The opposite of euphoria.

from Greek dusphoros 'hard to bear'