To stick something up your butt, generally drugs but can include anything.
The only way to do E is to boof it.

Where'd the kitty go? I boofed it.
by booferson March 24, 2008
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A knock off item, or an illegitimate imitation of a name brand item, most commonly used with designer clothes or jewelry.
“That Chinese website isn’t selling legitimate jerseys, they’re all boof jerseys.”

“I got a boof Rolex for only $30.”
by Tyrondre February 20, 2020
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a wolf rejected a jackrabbit dog so the stupid jackrabbit dog couldnt boof boof
by Baikin_1236 October 21, 2017
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Strong ass Weed, the type of shit that knocks you on your ass
I don't want friends, I want Audis (what?)
Smokin' on boof and it's Maui (ayy)
-Smokepurpp
by #253 October 11, 2018
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the act of consuming alcohol via the anus, for rapid buzz
e.g. Lance boofed a bottle of Old Thompson
by Fudgy Johnson September 20, 2004
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Smelled dat boof got me feinin
by iamSWISH November 9, 2014
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Damn, son. What is that smell? It smells like somebody boofed it
by Fhfhdh December 14, 2017
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