Brand name for Ibuprofen, a non-steroidal anti-inflamatory drug. Works by blocking the enzyme cyclooxygenase , which is responsible for the production of prostaglandins (an inflammatory molecule) through the arachadonic acid cascade. Although sold as a racemic mixture, the (S) isomer is most effective, although the (R) isomer is converted to the (S) isomer in the body and used. Used for the relief of minor pain, has the typical list of side effects which may actually be worse then the minor pain you took it to relieve. Works well to alleviate hangovers if taken before going to sleep, slightly less risky to the liver then Tylenol.

Referring to the heavy unfashionable winter jacket and patterned mittens Sanders wore to the inauguration of Joe Biden.

A great drug that despite common belief cannot relief misery, despair and anxiety.

To receive oral sex from a female. Dome, head, or a blow job. Relieves a head ache, reduces swelling. advil PM: head so good it puts you to sleep.

one day i went to the store, and i saw advil. he was ugly as a day but healed me in ways no one else could. who was he? my baby daddy. advil i love u come back

Slang term for Asians, usually derogatory. Stems from the Advil slogan, "Little. Yellow. Different."

a medicine that doesn’t cure shit