Top definition
The act of driving a long distance, usually over 100 miles, on a sudden whim, typically to an undesirable location. Often motivated by mental illness or drug usage.
"let's do a zito run to Payson" "You hear? Pres. bush did a total zito run to Baghdad this morning"
by TheHat160 May 20, 2008
Get the mug
Get a Zito Run mug for your sister Sarah.