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Acronym for You Only Live Once.

Now get off your computer and go outside.
George came to the party with the word Y.O.L.O. on his shirt and got things started.
by THC420 December 27, 2009
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One of the best things ever invented. The perfect way to kill off the retards in this world.
Person 1: I'm going to jump off a bridge 'cus you know, yolo.
Me: You know what, be my guest.
by Chrome shelled November 11, 2012
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a word of which means "you only live once" but actually means "you only get one life, so why not do these idiotic things that could shorten it, or even better get us jailtime for a large percentage of it"
anass rhammar: I'm gonna jump!

Willie stroker: no don't, you will die!

anass: YOLO !
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it is the most fucking annoying word in the world. people hate it. it is gay.
Guy 1: Yo sup

Guy 2: SMOKED A JOINT, YOLO

Guy 1: Fuck you
by TheWildGareBear June 20, 2012
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YOLO, short for "you only live once," is an Internet phrase that obtained a large following in late 2011 and early 2012. It used to be used to express appreciation of life's little things and opportunities, but has since been butchered by being used with any action or phrase.
"omfg lol just killed a homeless guy for another cardboard box #YOLO"

"lmfao i want to see if i can juggle soap in prison and get away with it!!!!11!1!1!!!1! #YOLO"
by CipollaM926 March 27, 2012
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An invitation for one or more person(s) to participate in anal sex.
Jeff: Hey, Janie. Yolo?
Janie: Yeah, come over at six and bring extra towels.
by The Impossible Derek March 19, 2012
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a 'word' little cunt twelvies use. yolo means you only live once which should actually means shut the fuck up before i shove my twelve inch cock down your yolo yodelling throat. fuck all you yolo twelvies.
Little faggot twelvie smoking cones: YOLO! :DD
Me: Shut the fuck up you little cunt. *smacks over the head with another yodelling yolo cunt*
by ranterlul August 20, 2012
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