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That's what's up 

Meaning that you fully understand and/or agree and find yourself excited about the idea or suggestion proposed.
Friend 1: "Yeah so I'm thinking we chill before, and then hit the club by 9. Got mad beer at the crib anyway"
Friend 2: "That's what's up"
That's what's up by KelsBels April 5, 2008

That's What's Up 

"You got accepted to Harvard? That's what's up, dude."

That's What's Up 

A way of agreeing to what the other is saying. Or if they ask you a question it can also mean that you are down to do what they're asking.
1:"Ay mayne, i got this killa, we blazinituptoday?"
2:"Shiiiit, that's what's up!"

that's what's up 

Something that is exciting, great, and agreeable.


cool the shit the bomb These are just a few synonyms.
that's what's up by dd3953 December 30, 2008

that's what's up 

Originated in Philadelphia circa 1998. When discussing events that are of intrest to both parties. The person that didn't know what was going down would say that's what's up.
usally rhetorical.
Frank:Yo! There's a big concert at the spectrum tonite?
Jonny: that's what's up!
that's what's up by HRM SMK April 2, 2008

That's what's up 

A phrase to show your acceptance and/or and or approval of an idea or event. Or... if used in certain situations a way of expressing your discontent caused by a person's actions, ideas, or events.
a)1: what's good my homie?

2: not much man, just been chillin.

1: that's what's up.

b) so you're gonna side with them over me, huh? That's what's up.
That's what's up by KingD303 June 16, 2016