Vade Mecum Share definition Flag A useful thing one carries with him/her at all times. Usually some sort of manual or book. This boy scout handbook has become my vade mecum since I lost my little brother in these woods a few years back. Vade Mecum by the pixeltarian October 11, 2006 0 0 Get merch Get the Vade Mecum mug. Buy Now — $32.95 See more merch