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High five.
Commonly used by Barney Stinson in the comedy series 'How I Met Your Mother'.
- I've managed to get the new job!
- Uptop!
uptop by earnnet December 9, 2012
Used as a friendly response to a greeting.
"Yow mi G"
"Uptop!''
Uptop by Crystalthegem March 18, 2019

uptop shit 

A small area in the mt airy section of a Philadelphia that spans from 1400 Vernon rd to 1500 Wadsworth ave
That's some uptop shit
uptop shit by Smittuptop April 9, 2017

Take it uptop 

Yo, his ass was straight wylin' so I had to take it uptop, early! Naa mean?
Take it uptop by Shortytuz November 21, 2004

All The Way Uptop 

Referring to the Neighborhood In Washington DC. The Top of DC, Uptown NW. Also known as the Gold Coast/ Shepherd Park. The Top of the DC Map. Defines as your location in dc as being at the top of NorthWest DC on the map.
My bro and them about to head uptown, All The Way Uptop.

Uptown girl

It is an excellent song by Billy Joel

And also it means a girl who is sophisticated and classy - in some cases snobby - but not all
Uptown girl by YASSS123 June 26, 2015