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A sexual move whereby during doggy style sex the penis, in one swift move, is removed from the vagina and reintroduced into the anus (also known as changing at baker street). The shock causes the recipient's head to rear up at which point the gentleman smacks it down with his fist as one would a miscreant pack animal. Hilarity ensues for all involved. Except possibly for the "mule-ee".
Dave: The girlfriend dumped me last night, mate.

Steve: Really, mate?

Dave: Yep. Tried the mule. She wasn't best pleased.
by Uncle Twatflaps October 25, 2006
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the butt of a gun.
to "hit someone with The Mule" is essentially pistol whipping, but it should be noted that when hitting someone with The Mule only the butt of the gun is used.
"Bitch wouldn't stop running her mouth so I had to hit her with The Mule."
by D. Wroughton July 26, 2009
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The tag given to the single 21 year old at a party who's sole function is to retrieve beer for underage people who don't like him.
Toby: You guys want a case? I'm buying if I can stay!

Franklin: Sure toolbag, just hurry I'm thirsty.
(Toby exits)
Franklin: The Mule FTW
by Birddog Dan January 31, 2011
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The Mule (2014): An Australian attempt at crime-drama / toilet-humor, a tale of loyalty, justice and perseverance through adversity as Hugo Weaving explores the question: what use is a search-warrant if you are unable to take a shit?
The Mule was really a shit movie
by Peculiar Musings March 08, 2015
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