The act of being so socially awkward and inexperienced when trying to enter a relationship; bad/awkward flirting; you fucktards who can’t talk to girls/boys without messing up somehow and making shit weird
I think Jim is having a case of relation-itis, why is that? Well he’s never dated before....

Bruh she ghosted me after three days, do I have relation-itis?
by SuperGlimpses (Dic)tionary February 9, 2018
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A made up disease which a person goes crazy for men.
It doesn’t have to be exactly that, it could also mean the opposite.
Person: are you okay?
Me: No… I have Men-itis.. and there are alot of hot men here
Person: Menitis..?
Me: I love men so much I want a dilf to hug me to badly
by TheRobloxMafiaMansimp August 20, 2023
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Joe has diarrhea, and keeps pooping his pants. Sounds like he’s got the bitch nigga itis
by Big_Dick_Johnson_69 July 31, 2021
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Amusement-itis is when you can’t seem to make someone laugh, even though you used to all the time.
Example
“I just said a joke” “yeah but it wasn’t funny” “ but I used to make you laugh all the time... oh no I’ve got AMUSEMENT-ITIS”.
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(n.) a serious disease where inflamation occurs in certain parts of the brain which causes people to read books or have the idea.
Due to a professor's teachings, I have become infected with read-a-book-itis
by anonymous_two September 23, 2008
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The desire to possess original online usernames for the purpose of looking cool in front of friends and randoms that honestly couldn't give any shits about the username you have.

Symptoms of OG-itis consist of, but aren't limited to: Spending your entire life savings on OG usernames and ditching friends you've known your entire life just because they had numbers, underscores, or hyphens in their username.
Friend: Hey dude wanna play some COD?
OG-itis Victim: Yeah sure on which account, Capture, Herb or Hyped?

Friend: Dude...you have OG-itis..
by 420BBQ@DQ May 3, 2015
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the disability that lolzd has, also the reason that he says "literally" all the time.
okay so the reason i say literally all the time is, because i literally have fortnite-itis.
by cocofruits March 21, 2022
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