Short for Rusty Dick Syndrome.

Occurs when someone has extremely dirty and/or inactive genitalia.
Lou cant get girls. He must have serious RDS.

Sorry son, your RDS is too severe. You have 6 months to live.

Ya got RDS.
by Steve K wussup August 25, 2009
I am sorry that I cant go drinking with you lovely ladies tonight. Alcohol aggravates my RDS
by knightofzion June 25, 2011
I almost fell on my face after trying to stand up from the porcelain god. I read for half an hour after pinching off a hot loaf and my legs were so numb I couldn't stand up. The RDS was so bad i had to use the cripple bar in the crapper just to pull my shorts up.
by Douglasazo January 12, 2006
Relevance Deprivation Syndrome
Oh yeah that Mark Latham failed Australian politician just has RDS
by TheChairmanMeow March 8, 2017
A serious condition where the affected get the uncontrollable urge to touch or grope those around them however can be treated with a harmless injection.
by Spaceship003 April 5, 2015
really dumb shit. Can also be used in the medical field as RDS syndrome
Guy 1 walks into a door

Guy 2: Did your RDS just kick in?
by medic_in_training November 11, 2010
Unfortuantely, the guy I dated last year suffered from a severe case of RDS.
by Fly Gal August 21, 2006