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1. Short for Phantasy Star Online
2. An addicting drug that is taken through the eyes, highly addictive in large doses, smaller doses cause intrigue
I'm having PSO withdrawals, i need a fix.
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Nov 23 Word of the Day
A massive dump that takes 10 to 15 times to flush.
After Thanksgiving, I had to Take a Trump.
by JRBIV December 11, 2019
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2
PSOS stands for 'purple shirt of sex' and is a reference to the purple button up shirt Benedict Cumberbatch wears in BBC Sherlock.
OH MY GOD SHERLOCK IS WEARING THE PSOS AGAIN.
via giphy
by Saucilicious January 18, 2017
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3
A great game avalible on DC, GC and Xbox.

I love it. Can't wait for episode 3.
PSO.. oh my god, who corrupted it!?
by Tekki January 16, 2004
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4
PSO stands for Phone Sex Operator and is a person who will engage in phone sex in exchange for money.
The PSO charged $1.99 a minute to have phone sex
by wildsidechicago August 25, 2004
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5
Potential Significant Other, referring to an individual not quite your significant other. Could pertain to a date, a crush, an unrequited lover, a stranger you'd like to marry, etc.
My PSO totally asked to borrow my pen in calc today.
by swtcaroline December 14, 2006
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