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TLDR: Older Brother

A little more detail if you like-
Onii can end with 3 different Japanese honourifics, -San, -Chan, or -Sama.
-San is the basic ending for the basic big bro.
-Chan is a more compassionate ending for Onii if you really love your big brother and feel emotionally attached to him greatly
-Sama is a bit of a formal ending for big brother, nothing too special.
My Onii-San is a cool bro
I really love my Onii-Chan!
Yes he is my Onii-Sama
by Rywen March 10, 2015
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Onii-Chan means "Big brother" in Japanese. Most people assume it's a mating call of some sort because of hentai but no that's just hentai. Lots of hentai has incest.
"Onii-chan! Drive me to my friend's house!"
by RigsSaysGoodbye May 04, 2018
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When a anime girl calls her older brother "onii-chan" it means get ready for insest.
Anime girl-"onii-chan~"
*1 day later* *INSEST* Anime girl- *moAnS*
by SeNpAi~~~~ August 11, 2019
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When an asian says onii-chan it means mating season has begun and she won't stop having sexytime until it's over or she is impregnated
Onii Chan Give it to me
by bock bock bock February 22, 2018
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