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TLDR: Older Brother

A little more detail if you like-
Onii can end with 3 different Japanese honourifics, -San, -Chan, or -Sama.
-San is the basic ending for the basic big bro.
-Chan is a more compassionate ending for Onii if you really love your big brother and feel emotionally attached to him greatly
-Sama is a bit of a formal ending for big brother, nothing too special.
My Onii-San is a cool bro
I really love my Onii-Chan!
Yes he is my Onii-Sama
by Rywen March 10, 2015
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3
Onii-Chan means "Big brother" in Japanese. Most people assume it's a mating call of some sort because of hentai but no that's just hentai. Lots of hentai has incest.
"Onii-chan! Drive me to my friend's house!"
by RigsSaysGoodbye May 04, 2018
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5
A strikingly sexy male friend, who all girls fawn over. A word used in replacement for the male friend's name whom you drool over so dearly. In Japanese, Onii-chan means older brother, and is a title of respect and in some cases, resentment. Onii-chan is a word commonly used during weaboos climaxing over hot characters in their favourite anime
Hands off! Lincoln is my Onii-chan!
by Lord Onii March 10, 2015
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6
The Japanese word for "fuck-buddy" most commonly used in anime.
"Onii-chan! Close your eyes and don't look ;)"
by Secretsneverdie December 16, 2017
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7
a japanese word meaning big brother for sonny i hope u find this

you know nothing baka
but onii-chan im scared ,

hello onii-chan
by 708 707s sis January 23, 2017
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