1) A girl that looses one of her shoes after a drunken night of debauchery and wakes up to do the walk of shame with only one shoe.

2) A girl that is such a dirty pirate hooker (see dirty pirate hooker) that you have to assume she has one peg-leg and therefore only requires one shoe.
One Shoe, I can't believe you took two guys to the bathroom of the bar, you must be a really big dirty pirate hooker, arr.
by W.A.M. August 27, 2007
A shoe that has lost it's SOLE mate, ha ha. A disgarded lonely shoe, that can be seen on any street across the nation, symbol of disposible society.
You know, there’s a lot of things wrong with the world, famine, war, slavery, rape,
abuse, drugs, the list goes on. But let’s not talk about them; let’s talk about the serious
stuff. For instance, The One Shoe.
by Beadle September 30, 2003
A person who when chasing down a Russian interior decorator loses one of their shoes in the snow.
Christopher Moltisanti: I'll leave you here you one shoe cocksucker!
by NewJerseyBoy August 14, 2010
Rebecca: Jenny is such a goody-two shoes, she is so annoying.
Uma: But her sister, Jessica, is a total rebel one-shoe. She always marches to the beat of her own drum.
by netflixxlove March 3, 2016
While driving, a male will remove one shoe, then sock, and then put the shoe back on the bare foot but placing the sock on his genitals to masturbate cleanly and discretely.
While being stuck in LA traffic, John decided to have a one sock, two shoes cruise to help pass the time.
by Mythattak May 22, 2017