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Most commonly found in nerds/geeks and is an extreme over reaction to any form of assessment in which they can study for

Nerd: "My brain is about to explode... I have been studying all day."
Random: "Dude, you need to find some medication for your serious case of OSD!"
by non_stop.dance_party September 02, 2010
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Over Sized Dick
"Did you ask me if his dick was small; it was an OSD girl"
by beenjordansince December 23, 2014
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Old School Dicks, an organization of older college males, who primarily get with freshman sluts. Originated in Texas, now growing world wide. Also known to be one of the most dangerous organizations in East Texas.
I'm a 27 year old college student and I can't wait till the new crop of freshmen girls come in next year, for I am O.S.D.
by J-Dubnac April 09, 2006
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OSD is anachronism for Obama Slobber Disorder: Used in a derogatory way to describe one who can not see Obama’s flaws due to their “slobberinglove affair with the man.
You OSD blinds you to the President's Socialist agenda.
by oramato March 31, 2010
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On some dumb shit
I really like him but I KNOW he’s osds
by BigNoo October 18, 2017
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