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street name for over the counter cough and cold tablets (coricidin - cough and cold) which contains DXM (dextromethorphan) which if abused (usually 8+ pills) will fuck you up severly! could cause hallucinations, good times, or death.
person: im gonna go steal some mofo's and get fecked up.
animal: right on
mofo's by god July 13, 2003

Slack ass Mofo's 

Slack arse whores who stay on break all day and hardly ever take any calls.
"Look at Eddy, Aubrey, Ian, Simmo, Brennan, Spada, Bartley, Connolly and Tristian. They are a bunch of slack ass Mofo's today."

"What you talking about fool, they is always a bunch of slack ass mofos".

Vegas Mofo's

Group of obnoxious and crazy Mofo's from Vegas that ride the dunes. Can usually be spotted out at Dumont, tearing up the razorbacks on either quads or MX bikes. Usually spotted riding 2 stroke 500's but sometimes can be spotted in a rail, or on your wife.
Was getting ready to sex it up with my girl and i asked her how she wanted it.

She screamed out.... "Like a Vegas Mofo!!"

I scratched my head and ask... "How is that?"

She YELLS.... "HARD and FAST, just like them "VEGAS MOFO's"
Vegas Mofo's by Vegas G September 9, 2011

Niall's mofo

A new name for Directioners.

When One Direction memeber, Niall Horan, tweeted about fans calling them "mofos." Many of the fans acted quickly, especially on tumblr. They decided that would call themselves Niall's mofos instead of Directioners.
Girl 1: OMG I'm a Directioner for life

Girl 2: Shut up, if you really were, you'd be calling yourself Niall's mofo.
Niall's mofo by Niall's Mofo November 8, 2012

mofo style 

Actions taking the form of that which is hardcore. Actions performed by a mofo (or mofo-king).
Dude, he just owned you mofo-style!
mofo style by Mofo Kings I and II November 17, 2004

shit bitch mofo shea bitch 

when somethings gone so wrong in so little time you can think of legitiment words for describing it.
jack: oh hey jill whats up?
jill: not much just , oh shit bitch mofo shea bitch!
jack: what happend?
jill: i just fell down the hill!