When a guy starts acting really crabby, and complaining much like a woman on her period.
Eric: "I am sick and tired of cleaning up your crap, Paul. Keep it on your side of the room!"
Paul: "Woah, sorry dude. No need to manstruate at me- I'll clean it up!"

James: "Dude, what's up with Jeff? He's been really crabby lately."
Harry: "Yea, I know. He's probably manstruating."
by this_is_my_pseudonym October 25, 2010
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To be a weepy, cranky, mopey little bitch of a man just like your ex girlfriend acted once a month. Before she left you. For your Dad.
You are crying so much, is it your time of month to manstruate?
by Uri Bent My Cock. January 31, 2015
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The male version of the menstrual cycle.
A man period.
The male version of PMS.
I'm cranky. I must be manstruating.
by Lancelot1 August 13, 2006
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(noun) man-stroo-ay-shun A period of time when a male bleeds from his anus due to excessive wiping. Due to the continuous need to wipe and resulting inability of the anus to heal, the bleeding usually persists for about a week. After a month or so, the male will forget the effects of over-wiping and assault his anus again to ensure cleanliness after a particularly wicked bowel movement which will initiate Manstruation again.

Due to the similar lengths of time/occurrence between this process and female menstruation, as well as the resultant mood swings and general "bitchiness" males display when bleeding from their ass that also accompany females bleeding from their vaginas, this is known as "Manstruation".

(verb) Manstruate
(continuous) Manstruating
"The running back's manstruation was affecting the effectiveness of his play because he was running like he just rode a horse for ten days straight, and felt like it too."
by The Wise Savage June 18, 2015
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A man's version of a period with involves random waves of unexplained anger that would appear to be for little to no reason.
"I think he was on his Manstruation cycle because he broke the remote for no reason".
by ThiccDaddy03 March 5, 2019
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Something that happens every other day, and is NOT the same as menstruation. It is when a man becomes irritable, experiences cramps and bleeds from his willy. As shops do not stock male sanitary products, the man often resorts to using tissues or bits of scrap cloth to absorb the bleeding. Unlike menstruation, manstruation happens every other day and only lasts around 10 hours.
"Woah Mike are you experiencing manstruation? Don't worry I've got some toilet paper in here somewhere."
by raddest_kid_around67 February 5, 2021
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When a man is having his “period.”
Glendolf is so emotional today. He must be manstruating. Manstruation is not his friend.
by Hootoohatty June 22, 2018
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