Make like a fetus and head out is a play on make like a tree and leave, referring to a fetus entering this world head first. It is a pun and means: go away! or leave now!
"make like a fetus and head out" he shouted whilst pointing at the door.
by Sircasm February 14, 2019
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Famously, one of Biff Tannen's taglines in Back to the Future movies. The other ones being "Shiiiit!" and "I hate manure!"
Young Biff: All right, I'll give it a look. Now why don't you make like a tree and get out of here?

Old Biff (hitting Young Biff upside his head): It's LEAVE, you idiot! "Make like a tree and leave!" You sound like a damn fool when you're saying it wrong!
by PancakeMonster83 May 4, 2016
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Originator of the Word: The Heretic Assassin

Meaning: A Dirty South New Orleans hood version of "Make Like a Banana and Split!" or "Make like a Tree and Leave" when somebody annoys you and you want them to part from your presence or when you are about to leave from someone's presence
Man when I realized that this dumb ass dude wasn't gonna conceive what I tried to teach him, i simple told the nigga to Make Like Michael Jordan and Fade Away! And he departed from me.
by The Saint from The 4 February 21, 2011
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Biff: Now why don’t you make like a tree and get out of here?

Old Biff: *slaps Biff* It’s “Leave” you idiot. “Make like a tree and leave”. You sound like a damn fool when you say it wrong.
by KnightofNerdom May 25, 2018
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