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Michigan State University. Found on the banks of the Red Cedar River in beautiful East Lansing, MI. Supporting a student population of over 45,000 it is the State of Michigan's largest academic institution.

Michigan State was Founded in 1855 after the passage of the Morill Act (providing free parcels of land for new public institutions). MSU was the first university to come into existence this way and is referred to as the "pioneer land-grant institution."

Known for its Division 1A sports teams, many top rated programs, and largest dormatory capacity in the nation, East Lansing can always be found on lists of America's best towns to live in for 18-24 year olds and lists of the nation's prettiest campuses.
Wow, I've never seen a campus as beautiful as Michigan State.
by Academic Type January 13, 2005
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2
A term for an extremely attractive and sexually active mother. She embodies everything that is erotic and has an insatiable appetite for younger men, mostly of her son's age. It has also been rumored that she has magical lady bits.
Guy 1: Man I just scored with a Ms. U last night, she could not get enough.

Guy 2: Tell me about it, I was with the OG Ms. U a while back, and she was dick hungry.
by jsphnemetz June 21, 2012
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3
Make shit up. The US ARCENT Intelligence Directorate modus operandi for any thing that needs an answer. This method is officially approved by the US ARCENT Chief of Staff.
Maj Wilson: "What's the enemy force disposition in the Rich Mountain Province?"

SPC Cowan: "Sir, the Alovian army has approximately 14,000 mechanized infantry troops in defensive positions through out the region."

Maj Wilson: "WTF? Where did you get that number?"

SPC Cowan: "MSU, sir."
by Task Force Swimley March 01, 2008
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4
Most Stupid User
The target user when you want a foolproof program
"even the MSU will understand this"
by PappaNiklas June 20, 2016
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Makin Shit Up! A liar, some one who for the joy of it tells out right blatant lies!
I call MSU!!! Your makin shit up!
by MaiTHAI October 19, 2006
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7
To lose a sporting event or game by a humiliatingly lopsided score, especially in an important game or one with national visibility.
( pronounced "emm-ess-yew" )
EX: "How bogus we got crushed so bad by Stanford."
"I know, we totally MSU'd the Rose Bowl."

EX: "I can't believe we made it to the Championship Game. I hope we don't MSU it."
by Spartoon April 14, 2016
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