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Abbreviation in both speech and text for "<i>modus operandi</i>" (Latin) or "mode of operation" (English). The term is used to mean either the way in which one does something, or his or her focus or goal/ambition in a certain aspect of life.

"Main Entry:
mo·dus ope·ran·di
Pronunciation:
\ˌmō-dəs-ˌä-pə-ˈran-dē, -ˌdī\
Function:
noun
Inflected Form(s):
plural mo·di operandi \ˈmō-ˌdē-, ˈmō-ˌdī-\
Etymology:
New Latin
Date:
1654

: a method of procedure ; especially : a distinct pattern or method of operation that indicates or suggests the work of a single criminal in more than one crime"

Straight from Merriam-Webster, folks. http://www.merriam-webster.com/dictionary/modus+operandi

The idiot that said, "<i>operandi</i> is not a Latin word" is incorrect and needs more thumbs down. That entry should be removed.
My M.O. is to make the author of definition #2 look like a fool. That is what I am "all about."

I educate people and correct mistakes in "wiki" slang dictionaries by editing and making my own entries that state corrections of previous ones, when aforementioned entries are stupid. That is my M.O.

My M.O. is humiliating people who think they know more than they do even though both they and I are anonymous.
by Anomalous Karma April 30, 2009
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M O is an abbreviation for Modus Operandi. which is Latin for Method of Operation or Mode of Operation

In criminal investigations, it refers to the criminal's methods whether murder or burglary or whatever as similar methods used in separate offences which could indicate the same person was responsible.

It doesn't have to pertain to crime. It can also be used to describe a person's 'trade mark' habits.
My girlfriend always fingers my a-spot when she gives me head. That's her M O.
by RoosterCranium September 21, 2009
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9
Slang for a homosexual- short for "homo".
"You have 15 Barbra albums? You are such a 'mo".
by Duncan January 28, 2004
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The place Homer goes to drink with his friends Lenny, Carl, Barney, and the bar flies.
Homer goes to Moes and buys a duff. OH YEAH!!!
by sir loin April 28, 2005
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Multiple Orgasm Syndrome -

An ever-looming threat that hangs around the corner for all of us. Happens whenever we see someone wearing a comically sexy outfit such as jorts or socks and sandals. Results in a lot of cumming and moaning and is uncontrollable.
"Bro you shouldn't wear those jorts you don't wanna give the ladies M.O.S."
by ahahano October 12, 2019
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