This is a district under the government of a prefect (or prefecture) in Greece. It's made up of a number of islands in the Aegean Sea.

According to Greek mythology, the god of the islands was called 'Lesbos.'

An ancient poet called Sappho wrote about love between women about 2700 years ago and that's where we get the term 'lesbian' from.

Apparently, Sappho's poetry was pretty hot stuff and the Christians didn't like it. Little of it remains today thanks to a policy of it being destroyed by those against it.
Greek 1: "Behold! Across the Aegean sail the lovers Clitus Enormos and Vulva Maximus from the islands of Lesbos!"
Greek 2: "I'm hard as a temple pillar already!"
by Wizards Sleeve June 2, 2005
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The feminine heteronormative equivalent of 'no homo'.

A colloquial expression, often used by chicks after “inadvertently” alluding to or engaging in a decidedly lesbian act. Use of this phrase automatically negates any lesbian ambiguity generated by said act, and thus, it is perfectly acceptable for two teenage chicks, OR a couple of middle-aged conservative mothers to scissor each other all night long, as long as ‘no lesbo’ is said soon thereafter.
Teenage Girl #1: That chick over there has a nice rack.

Teenage Girl #2: Yeah, I'd like to munch on her rug all night long.

*fist bump*

*Both girls look at each suspiciously*

Teenage Girl #1: No lesbo, though, right?

Teenage Girl #2: Yeah, no lesbo.
by sea.shells January 28, 2010
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A women who is homosexual. One that likes to have sexual encounters with other women. Gay women. (See lesbian)
That porn star that ate that other women is a lesbo!
by Nitemare January 19, 2003
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A derogatory word used against lesbians. No, not just any women that like women. The word is used against lesbians and lesbians only. Please do not use this term if you are not a lesbian. Same with the term “les”.
Have you seen the new girl? That haircut makes me think she’s a lesbo.
by Brielle_Rose September 28, 2021
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A derogatory slang term for lesbian (adjective or noun). Shortened from the word "lesbian," which is derived from the name of the island of Lesbos (Lésvos).
The word lesbo is insulting, so don't use it.
by Samanli November 9, 2006
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A slur used against lesbian people
"Wow that guy called her a lesbo, what a bigot."
by John Ficks June 11, 2021
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a Greek island located in the northeastern Aegean Sea. People from lesbos are called lesbians.

"The word lesbian is derived from the poems of Sappho, born in Lesbos, which contain powerful emotional content directed toward other females and have frequently been interpreted as expressing homosexual love."
That gurl lives in lesbos.
by XDHAI!!!!!! May 26, 2015
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