Top definition
1. A syndrome which, for some bizzare reason unknown to man, causes one to drool uncontrollably

2. A form of cancer and down syndrome combined that inevitably lead to drooling
"Yo Kyle, you have Kyle Syndrome"

"Kyle, stop drooling!!"
by I am the ASS December 02, 2007
Get the mug
Get a Kyle Syndrome mug for your Facebook friend Yasemin.