I don't give a shits 

An ailment that causes one to not care about the consequences of their actions or give up on their goals.

"Hey man, you're getting fat again. What happened to your diet?"
"The I don't give a shits came early this year."

I don't give a shits by Gleen707 April 26, 2019

I don't give two and a half shits 

You really, REALLY don't care about what someone just told you.

Brody: Hey, I just found this really funny video I wanna show you, it's about this-

Ryan: I don't GIVE two and a half shits, alright?!

I don't give two and a half shits by MCGONN June 17, 2009

I don't give two and a half shits 

Combining a reference to two and a half men and the fact that you care so little about what the other person's saying.

-Hey, guess what I was doing last night?
-You know what? I don't give two and a half shits!

I don't give two and a half shits by Deathgleaner May 24, 2010

I dont give 2 shits and a flying fuck 

not caring about someone, something, or situation.
but expressing your uncaring attitude beyond the standard "i dont give a shit."

I dont give 2 shits and a flying fuck.

I dont give 2 shits and a flying fuck by strawberrkillfruit December 18, 2010