The best way to respond to just about anything to frustrate the other person to giving up.
I ran for 30 minutes on the treadmill today.

I'm sure.
by I'm Sure January 15, 2019
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A warm greeting used upon being introduced someone. It is most often used in the context of a highly formal situation.
Madame: Miss Davis, Miss Miller.

Miss Davis: How delightful to meet you, Miss Miller.

Miss Miller: Charmed, I'm sure.
by Taran July 8, 2004
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An expression used by one individual to another, usually meaning that they don't trust you entirely yet, and if you fuck up once, there's no chance of getting any at the end of the night.
Sir: Nice to meet you.
Ma'am: Charmed, I'm sure.
Sir: So...do you like beastiality?
Ma'am: ...*walks away*
by ThatGuySteveO September 1, 2006
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Alternative: "I don't know"

In conversation, when the person speaking to you wants you to feel like you're part of the conversation, but doesn't want to give you an opening. This conveniently allows the speaker to continue to ramble on about something trivial while the other person can only stand there and take it.
I'm not sure what your favorite movie is, but mine is Garden State, and this is why...
by jaykay84 August 29, 2009
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1. An expression of support for an effort, organization or person. Often comes after a list of achievements.

2. A paraphrase of Patrick Baron's hopes for Pope Benedict XVI upon the naming of the pontiff on April 20, 2005.
"Radiohead is totally turning the tables on the music industry. They're letting people set their own price for the new album, even giving it away for free. And I'm sure they'll continue World Youth Day!"

“It means that he’ll continue the great work of Pope John Paul! I’m sure he’ll continue World Youth Day! And … he’s just an awesome holy man!”
by Ben Timberlake November 1, 2007
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That cartman says when he is asked if he is sure.
episode 1201
Butters:Are you sure we should be doing this?
Cartman:Butters, i'm not just sure, i'm HIV positive!
Butters: OH well i guess thats true..
by Samanthaa* March 18, 2008
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