1. The act of deliberately disconnecting a phone call.

2.Hanging out while stoned.
1. "If that bitch calls me again, I'm hanging up on her!"

2. "Matt and I are hanging up later, man. Wanna come?"
by J-Neeners December 1, 2008
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to kill yourself;to commit suicide
if they hit me with life I gonna hang up.
by bknyc December 4, 2006
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When someone does not want to have sex or engage in any form of sexual activity due to some emotional problem.
Summer: C'mon, old man, little boy, let's make an inter-generational sandwich!

Rick & Morty: Eww! Gross! DIsgusting! Put some clothes on for god's sake!

Centaur: Sexual hang-ups in the pleasure chamber are punishable by death!
by Traflorkian April 30, 2016
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To Retire, settle down.
It's based on the idea of an old gun slinger who finds true love and 'hangs up his guns' to become a farmer.

In modern usage, it could be said about a guy who has previously had lots of casual relationships, or considers himself a 'playa'
"I tell ya man this chick is sooo sweet!"
"So you gonna hang up the guns?"
"Holstering my weapon as we speak"
"Mug!"
by Lazy Diamond June 19, 2009
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An annoyed or embarrassed response to the stupidity or incompetence of another. Synonymous with "Shut the fuck up", or "Jesus, you're stupid". Derived from one man's inability to counteract the obliviousness of those around him, to which he blurted it out in frustration. Also, an appropriate reply to an unfunny or otherwise retarded joke.
Bo: "Boy, I have a lot of tools in my garage."

Me: "Hang up the phone, tubby."
by Captain Walleye July 23, 2008
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What is shouted at the moron driving a 4000 pound motor vehicle and attempting to talk or even text on their cell phone while in motion. These are usually people that cannot multi-task but are either too vain or ignorant to realize it. They are in need of support from the community to let them know what they are doing is going to get someone killed. This is done either with a middle finger, an angry look, a colorful suggestion in a loud voice or a bumper sticker telling them to "hang up and drive." Once being made aware, they should terminate their call immediately and put both hands back on the wheel and pay attention to traffic conditions.
"Hey, you just drifted into my lane because you are driving with your elbows while texting... HANG UP AND DRIVE!"
by Mojo12 August 11, 2009
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