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Female equivalent of beating up. Not so violent and involves a lot of pushing and the occasional pinch. From the series "Confessions of Georgia Nicholson".
Jes was duffing up on Ellen. Jes was winning.
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duffing up is the female equivelant of beating up, or kicking ass. It's not so violent in a sense, and to a certain degree. It usually involves excessive screaming, clawing, pushing, and shit-talking.
ali is effing duffing up mandy, alis guna win, mandys so screwed.
by Ali Lansing July 15, 2006
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