Throwing up (vomiting) into a toilet. So-called because your firm grasp on the rim resembles the bus-driver clutching his/her steering wheel.
The heat, the food, and the drinks combined in a bad way. I ran inside from the barbeque and started driving the bus.
by GoFigure September 2, 2005
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To vomit kneeling in front of the bowl of a toilette. Because you are holding the bowl with your hands, it looks like you are driving a bus.
by Doppelstern April 8, 2009
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When a male is having sex with a female in the doggy style position, the male presses his thumb against the girls butt hole. His hand and fingers should be spread across and grabbing her booty kind of like you would grab a steering wheel in a vehicle. Inserting the thumb is known as honking her horn as she will most likely yell upon insertion.
Dick and Jane were going at it doggy style when Dick decided to drive the bus to see how far she would let him go.
by GI75 December 19, 2006
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In the act of selling drugs, you end up driving around to several different places for very little profit.
"I'm driving the bus at this point since I've driven to Egypt and back all for a funky $20 profit!"
by MP$40 August 30, 2005
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Being in charge of a project or planned activity, whether work related or not.
WORK: “We need to all be on the same page with this project, so we need a good outline and a game plan.”
“What are you expecting me to do? You’re driving the bus!”

FREE TIME:“Hey, when are we meeting at the theater and which movie are we seeing?”
“Shoot, man, ask John. He’s driving the bus.”
by Nurse Kitten August 31, 2005
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When it is your turn to drive the carpool to work, school, sporting events, ect.
This is the week I am driving the bus to work so I know we will be on time for a change.
by Delow August 30, 2005
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the act of hurlage. Vomiting.

"Wow, was I ever driving the bus last night after that 5th Long Island Iced Tea"
by Zanner August 30, 2005
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