Generally, any antidepressant or antianxiety medication, especially one prescribed and taken every
day. "Crazy pills" is a light-hearted, self-deprecating way of talking about these medications with close friends, trusted acquaintances, etc., without bringing the associated (and unnecessary) social stigma along for the
ride. If used in conversation with a
person you do not know, the intended meaning may be lost.
Common examples: Zoloft (sertraline), Lexapro, Wellbutrin.
A
person you know and
trust: "What pills are these?"
"Those are my crazy pills."
"Oh, cool. What time are we having dinner?......."