The act of a man having his urethra swabbed by a qtip to test for S.T.D.s
Or just another name for S.T.D.s because you have to get the swabing.
Term made most famous by Sweedish tecno/folk/bluegrass band Rednex with there verson of the song Cotton Eye Joe in 1994. "If it hadnt been for cotton eye joe I'd been married a long time ago. Where did you come from where did you go?" "Where did you come from cotton eye joe?"
Since Rednex's release of there recording in 1994 the song and dance have been seen and heard in countless talent shows and school dances around the world. Song also featured on Kidz Bop childrens sing along cds.

If only they knew.
I went to the whore house and cotton eye joe caught a ride home with me.
by Johnny_Wayne January 20, 2010
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Deep throating a guy so he cums straight down your throat.

"Where did he come from? where did he go? Where did he come from, cotton eye Joe"
She doesnt like the taste of cum so she 'Cotton eye Joe's' so she doesn't have to taste it.
by Yadatonk June 30, 2019
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a guy named Joe with a cotton eye and nobody knows where he is or came from
Where did he come from, where did he go? where did cotton eye joe come from?
by solzness October 7, 2017
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Cotton eye joe is a mysterious person who has cotton for a eye, his name is joe and he comes and goes.
"Where'd you come from where'd you go? Where'd you come from Cotton eye joe
by verbazing June 21, 2019
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A common term for someone who takes/deals suspicious substances, typically cocaine, and thus has residue on their hands or body.
Bro! You've got cotton eye Joe fingers, go wash your hands!
by weriddreamer November 20, 2018
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