a phrase used by many people basicaly meaning say something and get your ass whipped. its usualy said by "gangster" people in areas with poverty.
I was looking at Tyrece in the hallway and he told me to run-up get done-up. im going to the guidance counsler!
by T-rizzle Dizzle January 17, 2009
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An question replaced "Hello" or "Hi" as the most popular form of casual greeting.
And the answer is from Chinglish, means "Study hard and make progress every day"
"What's up? Day day up!" example:

Person 1: What's up?
Person 2: Day day up!
by DWang2k August 11, 2014
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Basically furiousfade the youtuber made this famous. RUN UP GET DONE UP
"you seen that one dude talkin all that hot sh**, run up get done up vibes around this bih"
by trey555 May 21, 2021
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Whats up with me and you. When are you gonna let me get some.
Boy: Ayo, Whats up with the whats up?
Girl: Fuck outta here, I got a man. No Single Ladies shit.
Boy: ....Fraud.
by Ctfu February 10, 2010
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When you and the boys are getting ready "priming up," to slime up some bitches
"Yo Alex, you ready to prime up for the slime up?" I heard there are gonna be bad bitches at the party tonight.
by Ganja Man Ry June 14, 2019
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the act of hooking up with a chick to beat it up which then leads to the inevitable act of you busting a nut(skeet)
"Yo, did you hook up with _____ last night?"

"Man, you know how I do. I fucking beat it up and straight skeet it up!"
by David M. November 28, 2004
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Drunk and high...straight up. This usually occurs when one smokes a blunt directly after consuming a large amount of alcohol in a small amount of time.
Yo, yo, yo, yo......yo. I can't go to 7-11 yet because I am to' up from the FLO' UP. Goddamn, nigga, don't touch me.
by Douglas from Burnie June 29, 2007
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