A person held in low regard.

A person who is worthless.

Variant of dumb fuck or little fuck (guppies are little) or just plain fuck used as a noun.

Possibly of jail or penetentiary origin from the Eastern United States.
That little "guppy fuck" don't know nothin'.

Wait till I catch that little "guppy fuck" alone...

That guppy fuck of a doctor won't give me any drugs!
by The Nedster March 3, 2011
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Someone who buy stuff because everyone else has it usually to fit in.
Steve bought that iPod because he is a market guppy.
by CptnObvious999 January 7, 2006
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Semen or 'little swimmers' found in the gusset of a females underwear after a sexual encounter.
As soon as I finished fucking her in the toilet, her thong was back up and she was straight back to the bar carrying my gusset guppies with her.
by Joosty October 26, 2017
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It's a chick, hence the fish reference, that gulps down cum like guppies gulping for oxygen in the water.
That little whore is such a cum guppy, she will swallow every drop!
by Solomon Grundy August 9, 2006
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Another term for sperm that has been deposited into an anal cavity
Bob deposited a load of mud guppies behind ted's turd cutter last night.
by ben November 13, 2003
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