quack Share definition Flag 1. One who is of methamphetamine addiction. 2. Someone who is really fuckin weird 1. Don't get near that fool, he's a quack. 2. He bought doughnuts for his cat, what a fuckin quack. quack by Iron-man_matthew April 10, 2008 0 0 Get merch Get the quack mug. Buy Now — $32.95 See more merch