A commonly used word in high schools that means "Whats going on?" "Whats good?" or "Whats happening?"
Also sometimes abbreviated as 'Sup'
Also sometimes abbreviated as 'Sup'
Example 1
Person 1: Sup brah
Person 2: Nothin' much man. Just chillin'
Example 2:
Person 1: Yo man. help me out with dis!
Person 2: What's up?
Person 1: I need help with dis dumb english assignment!
Person 2: No worries bro. Here's my paper from last year!
Person 1: Sup brah
Person 2: Nothin' much man. Just chillin'
Example 2:
Person 1: Yo man. help me out with dis!
Person 2: What's up?
Person 1: I need help with dis dumb english assignment!
Person 2: No worries bro. Here's my paper from last year!
by YoloMan12345 September 27, 2018

a generlaised greeting, can be used in most situations but has only one correct response - i hate bottles
by idiot cat November 28, 2004

Me: What’s up?
Julissa: What do u mean what’s up see
Everytime I text u
It’s like I have to have a reason
Me: Relax all I said was What’s up to see how you were doing
Julissa: What do u mean what’s up see
Everytime I text u
It’s like I have to have a reason
Me: Relax all I said was What’s up to see how you were doing
by Anon9173638 April 26, 2020

The most lazy, and unoriginal way to engage a conversation. Used by people who are bored with whom they are talking to, or have nothing else to say.
"Hey man...uh....what up
by Samuek August 19, 2008

Used to mean "she/he/you is/are very attractive and I would very much enjoy making love to you." It is derived from "A Night at the Roxbury"
Steve: What's up? What's up? What's up? What's up? What's up?
Doug: Steve, slow down.
Steve: I can't help it man, it's hottie overload.
Doug: Just pace yourself.
Steve: Ok... What's up?... 2, 3, 4. What's up?... 2, 3, 4...
Doug: Steve, slow down.
Steve: I can't help it man, it's hottie overload.
Doug: Just pace yourself.
Steve: Ok... What's up?... 2, 3, 4. What's up?... 2, 3, 4...
by Tonberry2000 April 21, 2009

An interrogative expression used to request a clarification or repetition of something previously said. Used in place of "what?"
by Ian May 2, 2004
