Bitch is a compliment when used by females. Calling yo bestie a Bitch is a way of showing affection towards another female. Although, Bitch when used by males is a supreme insult towards all females.
D1) "Woah look there's a new bitch in the family!"
D2) "Working at night is such a bitch!"
D3) "Everyone was bitching about Addelyn last night!"
D4) "My big bitch is that there's nothing new in here."